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The levels of 1,25(OH) 2 VD are regulated by the circulating PTH concentrations [24], while the biological actions of 1,25(OH) 2 VD depend on the status of the VDR in the target tissues [25]

Some research suggests that diet modifications might help alleviate gut issues and improve behavioral outcomes, though obesity and nutrient deficiencies remain concerns

Research by Pickart and colleagues has characterized its effects across multiple gene expression families relevant to extracellular matrix turnover, cell-cycle regulation, and DNA repair markers (Pickart, Int J Mol Sci, 2018)

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