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Another important consideration in this regard is that drugs of abuse may compromise the integrity of the BBB, potentially increasing its permeability

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The scenario depicted, clearly indicates that GSH is a weighty protagonist of the huge network governing the decision between life and death, through the modulation of cellular redox state

Molecular cell research , 1869 (9), 119300

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Through the specific receptor TFR1 (transferrin receptor 1), circulating iron (Fe 3+ ) can be imported into the cell and stored mostly within ferritin (Fe 3+ ), changing to cytoplasmic iron (65)