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However, treatments with GABA, DSIP-CBBBP, and DSIP all resulted in increased struggle times compared to the model group, with CBBBP alone not showing a similar effect, indicating a differential impact on depressive-like behaviors and highlighting the potential therapeutic value of these treatments in addressing depressive symptoms associated with insomnia (Vargas and Perlis, 2020)

For practical investigation, DSIP's subcutaneous route and existing human data provide a starting point, limited as that data may be