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Furthermore, placental perfusion may cause thrombosis due to its low pressure and turbulent flow (181)

However, although the selective action of antioxidants in counteracting the production of ROS is an interesting therapeutic strategy for the treatment of hypertension, in patients with various cardiovascular risk factors and with probable, however realistic, irreversible oxidative damage, the only antioxidant therapy may not be sufficient to reverse the damage ( 5.3 Nutraceuticals actives Polyphenols play a key role in the therapeutic action based on nutraceutical use