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n=800) key readouts MASH resolution w/ no fibrosis worsening: 62.9% semaglutide vs 34.3% placebo 1-stage fibrosis improvement w/ no MASH worsening: 36.8% vs 22.4% Papers: Resmetirom Semaglutide #MASH #Semaglutide #GLP1 FDA Approves Semaglutide for MASH with Moderate-to-Advanced Fibrosis FDA grants accelerated approval to semaglutide (Wegovy) for MASH On Aug 15, 2025, the FDA approved Wegovy (semaglutide) injection for adults with MASH with moderate-to-advanced fibrosis, under the accelerated approval (See FDA announcement below.) The following is a summary of clinical trial data for resmetirom and semaglutide

Eur Respir J 2022

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You may not be approved for ongoing coverage if you dont meet certain benchmarks, such as losing 5% of your body weight when prescribed Wegovy for weight loss

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Before breakfast and food: Wait to have breakfast for at least 30 minutes after taking semaglutide up to two hours if you can