GLP-1-class drugs amplify this in one indirect way: they work largely by suppressing appetite, which can drive protein intake and overall calories very low if a person simply "isn't hungry." Under-eating protein while losing weight quickly is the single biggest driver of avoidable muscle loss
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A., Swaab, D
Available from: Bate A, Lindquist M, Edwards IR, et al
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When comparing patients who initiated treatment with exenatide (n=14,076, median follow-up: 969 days), to those starting dulaglutide (n=54,787, median follow-up: 948 days) or liraglutide (n=25,562, median follow-up: 1,007 days), no differences were found in the hazard of composite treatment for diabetic macular edema (DME) and/or proliferative DR: exenatide vs
