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Upon stimulation by cytokines such as Tumor Necrosis Factor-alpha (TNF-) or Interleukin-1 (IL-1), endothelial cells undergo significant changes, including the de novo synthesis and cell surface expression of adhesion molecules like E-selectin, ICAM-1, and VCAM-1 [1] [2]

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To determine the efficiency of leukocytes to perform an oxidative burst, TPA was used in order to activate the responsible enzyme system to generate ROS

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