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New evidence on the actions of GLP-1 GLP-1 is secreted by L cells located in the distal ileum and colon in response to nutrient ingestion

Human data is still limited, but the improved bioavailability helps explain why some patients can eventually reduce to three times weekly dosing

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Healthy fats may support GLP-1 response, though evidence is mixed and context-dependent

Our approach starting low and increasing gradually minimizes this

Semaglutide is FDA-approved for weight loss in adults with a body mass index (BMI) of 30 or higher, or a BMI of 27 or higher with at least one weight-related condition, such as high blood pressure, high cholesterol, or type 2 diabetes