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however, although much of the evidence indicates that lower levels of IGF-1 benefit enhanced lifespan, IGF-1 does play important roles in homeostasis and not just during childhood thus raising the concern of potential negative effects of excessive lowering of the growth hormone

It is prescribed alongside a reduced-calorie diet and increased physical activity to help reduce excess body weight and maintain weight reduction long term

doi: 10.1038/s41574-020-00411-y 2 JacksonVMBreenDMFortinJ-PLiouAKuzmiskiJBLoomisAKet al

GI intolerance with GLP-1 RA use is a big deal

Your nutrition plays an important role in how you feel day to day, especially when adjusting to a new medication

Current Zepbound labeling says the majority of nausea, vomiting, and diarrhea events occurred during dose escalation and decreased over time