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Some endogenous neuropeptides do cross via saturable transport systems, and there is speculation that DSIP may do so, but this has not been rigorously demonstrated for exogenously administered peripheral DSIP in humans

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"A lectin receptor kinase as a potential sensor for extracellular nicotinamide adenine dinucleotide in Arabidopsis thaliana"

[Google Scholar] 168.Eads J.R., Krishnamurthi S.S., Saltzman J.N., Bajor D.L., Vinayak S., Barnholtz-Sloan J., Meropol N.J., Markowitz S.D., Wang Z