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Wang W, Wu Z, Lin G, Hu S, Wang B, Dai Z, et al

Since then, there has been a rapid rise in the occurrence of birth defects of children whose mothers ingested isotretinoin

The placebo arm results for the efficacy estimand were generally similar, with some differences between trials observed for the reduction in triglycerides, fasting plasma glucose (FPG) and systolic blood pressure (SBP, Supplementary Material Table S3)

4 Changes in ingestive behaviour at week 6

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This combination of effects helps control blood sugar levels and reduces food intake, leading to weight loss