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however, upon activation via antigenic stimulation, VDR expression is rapidly upregulated [157,158,159]

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The OS likely induced by EtOH metabolism [292, 293] may stimulate the oxidation steps of the Maillard reaction to increase the production of advanced glycation end products (AGE)

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Interestingly, subgroup analyses of previous clinical trials suggested that the beneficial effects of statins could extend to mechanisms beyond cholesterol reduction