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2a and ESM Table 2)
Insmeds Iplex however was an IGF-1/IGFBP-3 complex called mecasermin rinfabate (iPlex TM ) [90] designed to better mimic IGF-1s natural state and thus reduce side effects whilst also increasing its circulatory half-life [91,92]
Warning: Keep out of Reach of Children
Understanding these differences informs realistic expectations about treatment experience and effectiveness
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