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Progressive overload will be limited
Nat Rev Neurol 14(10):577589 Klemmensen MM, Borrowman SH, Pearce C, Pyles B, Chandra B (2024) Mitochondrial dysfunction in neurodegenerative disorders
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In conclusion, while GLP-1RAs and GLP-1/GIP dual agonists offer significant clinical advantages, ongoing research and vigilant monitoring of their adverse effects and safety are essential for optimizing their therapeutic application.229,230 Conclusion In summary, GLP-1RAs and dual-receptor agonists targeting both GLP-1 and GIP receptors have introduced significant advancements in the management of endocrine and metabolic disorders and their associated complications, establishing themselves as central therapeutic modalities within this domain