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Summary: GLP-1 receptor agonists are not licensed for anxiety treatment and lack established evidence for direct anxiolytic effects, though some patients may experience secondary psychological improvements through metabolic health gains

Portal GLP-1 administration in rats augments the insulin response to glucose via neuronal mechanisms

Once denatured, the peptide loses its specific biological activity

For most individuals, side effects are usually more prominent shortly after injecting the medication and wear off as the week progresses

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