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GLP-1, the second incretin, was discovered in 1987.GLP-1 stimulates insulin secretion in a glucose concentration-dependent manner at glucose level above 4.3 mmol/l
Other antidiabetic drugs such as DPP-4 inhibitors and SGLT2 inhibitors could also be a promising option and further studies with histological outcomes are awaited [115, 116]
Improved glycaemic control may reduce vascular complications that contribute to cognitive decline, whilst potential neuroprotective effects could directly influence disease progression
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[DOI] [PMC free article] [PubMed] [Google Scholar] 302.Selo MA, Sake JA, Ehrhardt C, Salomon JJ
La silhouette a une apparence plus harmonieuse, plus musculeuse
10.1073/pnas.0237106100 Proc
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