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A phase II study on safety and efficacy of high-dose N-acetylcysteine in patients with cystic fibrosis

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Here, we present cryo-electron microscopy structures showing that GLP-1(9-36) binds to an atypical site composed of the upper halves of transmembrane helices 1 (TM1) and 2 (TM2), extracellular loop 1, and the extracellular domain, distinct from the binding site of GLP-1(7-36)

All findings are limited to laboratory and experimental settings and do not indicate clinical performance

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