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The main mechanism of action of Phentermine/Topiramate extended release(ER) is possibly the alteration of various neurotransmitters, including inhibition of voltage-dependent sodium channels, glutamate receptors, and carbonic anhydrase as well as potentiation of -aminobutyrate activity (83).Two large randomized, double-blind, placebo-controlled trials took place (EQUIP and CONQUER) followed by a 2-year extension trial (SEQUEL)

3.2.2 Detoxification pathway impairment 3.2.2.1 Cytochrome P450 system dysfunction EED exposure creates a dual dysfunction within the cytochrome P450 system

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We have also recently introduced Lipotropic (MIC) injections in our IV lounge

Mohsen S, Mahmoudian S, Talbian S, Pourbakht A