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There is no downtime either way

Evaluate other contributing factors

found no significant adverse effects in mice, suggesting its potential as a safe natural antibiotic (Cha et al., 2012)

Additionally, this delivery method offers slow release over a 5-7 hour period

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An animal study showed that NAC increased histamine release in conjunction with fluoride.[ref] In people given IV n-acetylcysteine in a hospital setting for acetaminophen poisoning, about 8% of the patients had an anaphylactoid reaction, defined as cutaneous (urticaria, pruritus, angioedema) or systemic (hypotension, respiratory symptoms) within five hours of receiving the IV