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This means that despite fasting before the surgery, there is a potential risk of pulmonary aspiration (stomach contents such as food or liquid get inhaled and enter the lungs and windpipe)

Notably, even after stopping the drug, some weight loss benefit persisted long-term, albeit much weaker than with continued treatment

That's a powerful idea in early research and powerful is precisely why it isn't something to experiment with on your own

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Infect Immun 90(5):e0010322 Kelley N et al (2019) The NLRP3 inflammasome: an overview of mechanisms of activation and regulation

This could potentially lead to early puberty and compromised adult height without treatment (67, 72, 227)