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They previously published results from a study in children, where the insulinoma is congenital

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By selectively blocking NNMT, 5-Amino-1MQ is investigated for its ability to preserve cellular NAD+ pools, reduce methylation of nicotinamide to inactive 1-methylnicotinamide (1-MNA), and enhance sirtuin activity and energy metabolism

Endocrinology 130:249256 Drube J, Wan M, Bonthuis M, Whl E, Bacchetta J, Santos F, Grenda R, Edefonti A, Harambat J, Shroff R, Tnshoff B, Haffner D, European Society for Paediatric Nephrology Chronic Kidney Disease Mineral and Bone Disorders, Dialysis, and Transplantation Working Groups (2019) Clinical practice recommendations for growth hormone treatment in children with chronic kidney disease