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The findings from this analysis can have important clinical implications, considering that the daily duration of off-time for patients with Parkinsons disease can negatively impact their quality of life and that even a small change in the UPDRS motor scores can be clinically relevant [12, 23]

Patent 6,268,343

10.1016/j.semcancer.2020.11.020 [DOI] [PubMed] [Google Scholar] De Greef, D

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