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The RhoA/ROCK pathway plays a significant role in the differentiation of L-cells and other secretory cells by regulating cytoskeleton dynamics and YAP signaling
GLP-1 receptor agonists induce growth hormone secretion in healthy volunteers
These tissue changes create a depot that traps medication, releasing it erratically rather than smoothly
By lowering inflammatory markers and oxidative stress
The presence of these GLP-1-positive cells was consistent in rats with the mucosal expression of the key enzyme for proglucagon processing into GLP-1 (i.e., Pcsk1/3 coding for PC1/3) and of Pax6 , required for L cell differentiation (Supplementary Fig
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