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It was first studied in Honduras as a treatment for psoriasis [134]

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M., Kornelis, D., Van Marck, E

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In response to inflammation and OxS, the activated HO-1 is a powerful down-regulator of pro-coagulant factors to prevent thrombotic events, endothelial injury from vascular inflammation, resolve FeRD and reset HMRD in COVID-19 and PASC patients 27,46