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demonstrated, in addition to higher weight loss in the group treated with high-dose liraglutide 3.0 mg/day for 32 weeks, significant improvements not only of fasting glucose and HOMA-IR, but also of the post-load glucose measured by OGTT, OGTT-derived insulin sensitivity index (SIOGTT), and corrected the early insulin response to a glucose challenge (IGI/HOMA) compared to placebo [62]

Why B12 is added The addition of B12 serves multiple purposes

The median maximum excess weight loss percentage (%EWLmax) was 47.5%, but the final median %EWL decreased to only 24.2% after long-term follow-up (up to 19 years)

10.1016/j.diabres.2016.04.046 78 SattarN.LeeM

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This method requires patience