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Understanding cellular redox homeostasis: a challenge for precision medicine

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Brufani M, Figliola R

Besides, by upregulating the cytochrome c oxidase 2 (SCO2) (167), TP53 initiates several transcriptional programs to promote the expression of genes related to mitochondrial biogenesis (168), such as apoptosis-inducing factor (AIF) (169, 170) and ferredoxin reductase (FDXR) (171)

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Sacai H, Sakoori K, Konno K, Nagahama K, Suzuki H, Watanabe T, Watanabe M, Uesaka N, Kano M (2020) Autism spectrum disorder-like behavior caused by reduced excitatory synaptic transmission in pyramidal neurons of mouse prefrontal cortex