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Pernicious anaemia is caused by a deficiency in vitamin B12, due to atrophic gastritis, an autoimmune condition (immune system destroys self), in this case the parietal cells of the stomach that produce intrinsic factor, a glycoprotein that binds to vitamin B12 in the stomach and is essential for normal absorption of vitamin B12 in the small intestine into the blood
This multi-target intracellular signalling profile accounts for its consistent positive results across tendon, ligament, muscle, bone, skin, and gastrointestinal tissue repair models in the published literature
The rather poor performance of HDL raising medications has led to a gradual revision of the idea that HDL is good for you
Diabetic Ketoacidosis (DKA) is a serious and potentially fatal acute complication of diabetes mellitusmost commonly seen in Type 1 diabetesresulting from absolute or relative insulin deficiency combined with increased levels of counter-regulatory hormones (glucagon, cortisol, catecholamines, and growth hormone)
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