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Long-term exposure to UV radiation can induce inflammation and enhanced skin fibroblasts which can produce SCF that can bind to its receptor (c-KIT receptor or more specifically m-KIT receptor) and therefore melanin production through the activation of tyrosine kinase paths in melanocytes (Yuan and Jin, 2018

Given that anthocyanin contents are increased in response to various pressures, it is possible that the GSTs implicated in anthocyanin accumulation are likewise sensitive to both internal and external influences

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The endothelial cell population was subclustered separately at Leiden resolution 0.9, and annoated using known marker genes

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