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doi:10.1155/2015/648108 [28] Biological activity of human plasma copper-binding growth factor glycyl-l-histidyl-l-lysine

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Simultaneously, catalytically produced hydrogen peroxide (H 2 O 2 ) activates the protein transient receptor potential melastatin 2 (TRPM2) ion channel, promotes calcium influx, activates macrophages, and induces systemic immune response (Fig