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( Epub 2013 Jul 8

Testosterones conversion to dihydrotestosterone further enhances this inhibitory effect, reducing CRH and AVP mRNA expression in the PVN, decreasing POMC mRNA in the pituitary, and enhancing GR-mediated feedback 83

A multicenter, randomized, double-blind, placebo-controlled Phase 2 clinical trial (EudraCT 2007-0006731-31, NCT00777140) evaluated the safety, tolerability, and potential efficacy of DFO in patients with acute ischemic stroke in the middle cerebral artery region

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