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People of thiamin deficiency include those affected by: pregnancy chronic illness inadequate dietary intake alcoholism bariatric surgery chronic diuretic therapy Prolonged, untreated thiamin deficiency may lead to Wernicke-Korsakoff syndrome, a disorder that can affect people with chronic alcoholism, gastrointestinal disorders, or AIDS

Expression of the Bcl-2 protein family prevents the induction of apoptosis by a variety of oxidative stresses, including ionizing radiation, heat shock, or inhibition of GSH synthesis

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Jones, Ghassemzadeh 2018)

[9] Signs and symptoms [edit] In many people, symptoms are present for a considerable time before diagnosis