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These increases are offset by a decrease in toxicology costs of $2,738,000 as a result of IND-enabling studies completed in the prior year for inclusion in the CRB-601 IND filing and a decrease in compensation costs of $1,328,000 as a result of reduced headcount

Diagnosis is primarily clinical, with quantitative sensory testing used selectively in specialized settings

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Also it is good to know that agar (not agarose) is ionic so we cannot use it for pH measuring

References "Clinical Applications of Radiofrequency: Nonsurgical Skin Tightening (Thermage)," Clinics in Plastic Surgery , April 2009