Aardvark Therapeutics Sector: Oral gut-restricted bitter taste receptor agonists for hunger suppression HQ: San Diego, CA Year Founded: 2017 Origin Story: Aardvark Therapeutics was founded around a mechanistically distinct hypothesis: rather than suppressing appetite like GLP-1 drugs, the companys lead compound activates bitter taste receptors (TAS2Rs) confined to the gastrointestinal tract to trigger local release of satiety hormones, targeting hunger itself without systemic drug exposure
Such results, along with evidence of cardiovascular benefits (e.g
10.1155/2019/1968785 59 ZelnikerT
Without medical oversight, patients are more likely to miss key labs, struggle with side effects, or stop treatment early due to avoidable issues like incorrect dosing or lack of support
Its important to talk with your primary care provider before trying any supplement promoted online
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