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In essence, LL-37 converts normally non-immunogenic self-DNA into a powerful trigger for autoimmune activation

Healthy-volunteer studies reported changes in attention, operator performance, EEG measures, or functional connectivity after intranasal exposure [1] [2]

Lancet 2020;395:497506 22

Neither is approved for human use by the FDA or any other major regulatory body, and the findings below come from laboratory and animal studies

Bromelain Bromelain is a plant enzyme naturally found on the stem and fruit of the pineapple plant

Cells were incubated with the fluorescent probe (FITC)-labeled peptides at different concentrations for 4 h with minimal cytotoxicity (Figure 3A)