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Mild constipation may improve with hydration, fiber, movement, and clinician-approved support

Patients should increase home glucose monitoring frequency during the transition period and work with their healthcare provider to adjust or initiate alternative diabetes medications as needed

In the Phase 2 trial, 72% of participants who had prediabetes at the start had normal glycated hemoglobin levels at 48 weeks, compared to just 22% on placebo

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In contrast, a multicenter retrospective cohort study, including a higher-risk population (23% with CKD) reported slower eGFR decline and lower risks of CKD progression and doubling of serum creatinine among SGLT2 inhibitor users compared with GLP-1 receptor agonist users

GLP-1, or glucagon-like peptide-1, is a hormone that plays a significant role in regulating appetite and glucose metabolism