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Similarly, a significant elevation was measured in the permeability of targeted ibuprofen-coupled nanocarrier 3-PLG-ibu-A-GSH (P app : 27.70 10 6 cm/s) compared to the non-targeted 3-PLG-ibu (P app : 8.29 10 6 cm/s) polypeptide in the 24-h assay (Fig

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The mean population PK parameters used for these simulations were estimated in the reference publications describing the respective PK model for each formulation (Table 1) [15, 18, 19]

The injection sites were guided by a custom-made predesigned grid [Figure 1], which ensured the injections were adequately spaced and the projected cone of lipolysis had a minimal overlap ensuring a smoother transition into the zone of neighboring injection

6), comparisons between fly strains and between wasp strains were made using general linear models with quasibinomial errors