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The top risk factors for kidney disease are high blood pressure (hypertension), diabetes (type 1 or type 2), family history of kidney disease, smoking, obesity, advanced age, cardiovascular disease, and high cholesterol

IL-1RA dampens the pro-inflammatory effects of IL-1, preventing excessive inflammation and mitigating neuroinflammatory processes associated with neurological disorders (reviewed in: 39 )

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Epithelioids support genetic manipulation and enable the study of mutant cell competition and selection in three-dimensional epithelia, and show how anti-cancer treatments modulate competition between transformed and wild-type cells