However, any rectal bleeding warrants prompt medical assessment to identify the underlying cause, which may include haemorrhoids, inflammatory bowel disease, or more serious conditions
[11] Compounded GLP-1s: No Longer Available The FDA resolved the tirzepatide shortage in late 2024, ending compounding allowances: Compounded tirzepatide: No longer legally available from compliant pharmacies (as of March 2025) Compounded semaglutide: Also no longer available after shortage resolution FDA enforcement: Warning letters issued to compounders
Simplify instead of giving up altogether
Severe stomach pain that will not go away can be a sign of pancreatitis and needs urgent attention
This can also happen after stopping other GLP-1 or related medications, including Wegovy, Mounjaro, and Zepbound
While routine liver function testing is not standard for all patients on semaglutide, those with known hepatic disease may benefit from periodic assessment of ALT, AST, alkaline phosphatase, and bilirubin levels