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Common symptoms include a frequent and urgent need to urinateoften with only small amounts of urine each timeas well as a burning or stinging sensation during urination (dysuria)
HbA1c HbA1c 490% HbA1c1-2200mg/dlHbA1c 6.5%126mg/dlHbA1c 6.5% C C0.6ng/ml CPICC/1000.80.8-1.2GLP-11.2GLP-1 3 320130 3 GLP-1GIP 180kcal112 11/ MET33METs3METs20120-301214METs6METs30 20112 1350ml122-3 HDL 1 300-350mg/dlHbA1c 1034 21 LDL1st choice 1eGFR 30ml//1.73m 2 23 500mg/1500mg/2250mgeGFR4560ml//1.73m 2 1500mg/3045ml//1.73m 2 750mg/ 32 DPP-4 SGLT2 SUGLP-1GIPDPP-4DPP-4GLP-1 SGLT-2DPP-4SGLT2 SGLT2eGFR30ml//1.73m 2 SGLT2DPP-4 SGLT-2 DPP-4 2711 43 GLP-11GIP GLP-1 12BMI 32SGLT2DPP-43GLP-1DPP-4 GLP-1C0.6ng/mlC0.8 11 120m30 GLP-1GIP 5 SUSU244 SU20mg0.25mg80mg2mgeGFR 30ml//1.73m 2 HbA17 SUSUSU4 1250mg/dl2350mg/dl3412Kg/ 1123456DM 80120mg/dlHbA1c30%702 GLP-111 51 1.528.0%7.5%8.5% SUSGLT2 C WEB
Molecular docking was performed using Maestro by Schrdinger suite to investigate the binding modes of sertraline, fluoxetine, and citalopram to MRP1 and MRP7 (Figure 3)
Therefore, targeted enhancement of the GSH system along with prevention of ferroptosis in the myocardium is a promising therapeutic strategy
These symptoms could indicate infection, dehydration, or an unrelated gastrointestinal condition that requires treatment beyond GLP-1 management
