Overall, the certainty of the evidence for the evaluated outcomes was rated as low or very low due to study limitations and imprecise estimates
Nat Commun 15 , 6941 (2024)
These compounds offer distinct advantages over their peptide-based counterparts, including oral bioavailability, improved patient adherence, and the potential for broader therapeutic applications
Therefore, it is very likely that the semaglutide included in our analysis was prescribed as Ozempic, which is indicated for blood sugar control in type 2 diabetes. Upon analysis, researchers found that participants with diabetes taking a GLP-1 medication had a two-fold higher risk of developing nAMD a type of AMD where malformed blood vessels grow underneath the retina, causing fluids to leak into the macula of the eye
Your body just needs those hormones replaced
Clinically, it is mainly used to treat T2DM and causes weight reduction when used in large doses (3mg/day) (83)