The activation of endothelial cells in association with the fibroblasts may lead to a strengthened skin barrier and increased skin elasticity, as well as potential acceleration in tissue repair
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Although silencing the gene UL39 can limit the proliferation of oncolytic HSV-1 after injection, enhancing the safety of this oncolytic virus in clinical applications, the tumor-killing effect of this oncolytic virus is also restricted, requiring a larger dosage and multiple injections to achieve the desired effect
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