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Experimental data also indicate interactions with lipid peroxidation by-products such as 4-hydroxynonenal, a reactive aldehyde implicated in cellular stress responses

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The firs The title of this article states a relationship as though it were settled fact: that MOTS-C regulates AMPK activity when a cell is under energy stress

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Moreover, the glucagon/T3 conjugate effect is supported by the uncoupling protein 1-mediated thermogenesis, enhanced FGF21 secretion and biased by PGC-1 cofactor signaling