This process results in DNA point mutation and breaks, in addition to micronucleus formation and chromosome breakage (4, 22, 66)
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The enzymatic activities of Glutathione Peroxidase and Glutathione Reductase were determined with the following kits (from Cayman Chemical): Glutathione Peroxidase Assay Kit # 703102 and Glutathione Reductase Assay Kit# 703202, according to the manufacturer's instruction
They restore function
Next, assessment of the demyelinated area by LFB/PAS showed significantly reduced damage in the lumbar spinal cords of UAMC-3203 treated mice compared to vehicle or Fer1 treated mice (Fig
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