Phase 2 reported -24.2% body weight at 48 weeks at 12 mg, and Phase 3 TRIUMPH-4 reported up to -28.7% at 68 weeks at 12 mg
Along with these observations, calcitriol is known of influencing immunity regarding anti-inflammatory responses, tolerogenic actions and the prevention of immune overstimulation [68]
World J Gastroenterol 17:27232733
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however, their efficacy is limited [6, 7]
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