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Between 2024 and 2025, 13 major deals valued at $13.6 billion focused on multi-target regimens combining GLP-1s with agents such as amylin, myostatin, or calcitonin analogs

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Change in the healthcare space cannot be easily achieved, as it often requires changing federal and state laws, conducting a multitude of bureaucratic meetings to get everyone on board, and adjusting workflows for those who deliver care

In clinical trials, side effects tended to occur within the first weeks of starting therapy and with dose escalation, but they generally improved with time on a stable dose

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