The only conclusions that can be drawn by reviewing the existing literature at this point seem to be 1: The bending rigidity of red blood cells is reported over a large range, from 3 k B T to about 100 k B T, which does not depend on the technique 2: The spread in values cannot be explained by a length scale dependence of , as techniques which measure on large length scales report small and large values and vice versa 3: Techniques that isolate the RBC cytoplasmic membrane and only measure of the RBC cm report very small values, between 46 k B T 4: Because of these measurements, the contribution of the spectrin network is likely negligible as there are measurements of entire RBCs which also report such small values
MDPI, Cani, Patrice D., and Claude Knauf
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