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Mice treated with a metalloproteinase that cleaves an IGF-binding protein and decreases IGF-I bioavailability have a 38% longer lifespan and a lower tumor incidence

doi:10.1016/j.mrgentox.2008.10.008

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In addition, Studies on the regulation of ferroptosis by herbs or herbal extracts at different stages of NAFLD development to achieve intervention remains inadequate, and the related mechanisms need to be further explored as well

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