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Of the four human CYP3A enzymes identified, CYP3A4 is primarily relevant for drug metabolism, which is involved in the metabolism of approximately 90% of drugs in the gut (van Herwaarden et al., 2009)

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MIND diet and cognitive performance in older adults: a systematic review

Green et al., 2024

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After years or decades of self-doubt, shame, and stigma, they say the drug feels like validation: their inability to lose weight long-term was never a matter of self-control