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In the original healthy-adult study of albumin-binding CJC-1295, single subcutaneous doses raised mean plasma GH 2- to 10-fold for six days or more and mean IGF-I 1.5- to 3-fold for nine to eleven days, with an estimated elimination half-life on the order of roughly six to eight days a pharmacokinetic profile measured in days , not minutes

Precautions: As with all diabetes medications, individuals with history of pancreatitis should use linagliptin with caution, as there have been reports of pancreatitis associated with DPP -4 inhibitors [11]