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Despite demonstrating robust glycemic efficacy, both agents were eventually discontinued due to distinct tolerability and safety concerns, diverging in severity and clinical implications

Magnesium deficiency (hypomagnesemia) has been associated with insulin resistance, impaired glucose tolerance, and increased cardiovascular risk

It serves several functions, including fermentation of food, protection against pathogens, immune response stimulation and vitamin production

The New England Journal of Medicine

Since they debuted, injectable GLP-1 drugs like Ozempic have been in high demand

"We've got the four pillars we rely on, and if you think of them as legs of a chair, every time you take one of them away, things don't work as well," Basilico explained